Waldenström Macroglobulinemia: Relapsed/Refractory
The term “relapsed” refers to disease that reappears or grows again after a period of The absence of disease. Remission does not necessarily indicate that a person is cured. Patients may have complete or partial remission..
The term “A cancer that is resistant to treatment.” is used to describe when the lymphoma does not respond to treatment (meaning that the Abnormal cell growth that cannot be controlled by the body's natural defenses. Cancerous cells can grow and eventually form tumors. cells continue to grow) or when the response to treatment does not last very long.
For patients whose disease relapses or becomes refractory, secondary therapies may be successful in providing additional remissions. Some of the previous therapies discussed can be used or reused depending on a patient’s age, length of remission, stem cell transplant eligibility, and previous toxicities encountered. Additional therapies to treat relapsed/refractory Waldenström macroglobulinemia include:
- Everolimus (Afinitor)
- Ofatumumab (Arzerra) for patients who are intolerant to rituximab
- High-dose Treatment with drugs to stop the growth of rapidly dividing cancer cells, including lymphoma cells. followed by an A type of bone marrow or stem cell transplantation in which a patient receives his or her own cells. (patients receive their own stem cells) or A procedure in which a patient receives bone marrow or stem cells donated by another person. (patients receive stem cells from a donor) stem cell transplant in select patients